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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN5
All Species:
27.27
Human Site:
Y468
Identified Species:
54.55
UniProt:
O15484
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15484
NP_004046.2
640
73169
Y468
T
D
Q
P
E
G
R
Y
V
I
I
P
T
T
F
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
Y467
K
Y
L
K
K
G
N
Y
V
L
V
P
T
M
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542293
640
73142
F468
T
D
Q
P
E
G
R
F
V
I
I
P
T
T
F
Cat
Felis silvestris
Mouse
Mus musculus
O08688
640
72936
Y468
T
E
L
P
E
G
R
Y
V
I
I
P
T
T
F
Rat
Rattus norvegicus
Q8R4C0
640
73046
Y468
T
E
L
P
E
G
R
Y
V
I
I
P
T
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
L252
P
G
H
T
G
D
F
L
L
R
V
F
T
D
V
Chicken
Gallus gallus
Q92177
810
93542
Y547
F
R
L
P
P
S
E
Y
V
I
I
P
S
T
Y
Frog
Xenopus laevis
NP_001080808
642
73235
Y468
I
D
L
K
E
G
R
Y
V
V
I
P
T
T
F
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
Y468
K
E
L
K
E
G
R
Y
V
I
I
P
T
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
Y525
F
K
L
P
P
G
H
Y
L
I
V
P
S
T
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
G479
H
L
Q
S
L
P
R
G
R
Y
L
L
I
P
T
Sea Urchin
Strong. purpuratus
XP_792213
642
72430
Y466
S
T
L
L
R
G
R
Y
I
V
V
P
T
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
N.A.
92
N.A.
92.1
90.6
N.A.
51.4
30.8
73.9
71.6
N.A.
30.7
N.A.
40.1
47.6
Protein Similarity:
100
65.5
N.A.
95.6
N.A.
96
94.8
N.A.
57.3
46.9
86.2
83.8
N.A.
45.2
N.A.
57.2
64.9
P-Site Identity:
100
40
N.A.
93.3
N.A.
86.6
86.6
N.A.
6.6
46.6
73.3
73.3
N.A.
46.6
N.A.
13.3
40
P-Site Similarity:
100
60
N.A.
100
N.A.
93.3
93.3
N.A.
20
60
80
80
N.A.
66.6
N.A.
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
0
9
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
25
0
0
50
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
17
0
0
0
0
0
9
9
0
0
0
9
0
0
75
% F
% Gly:
0
9
0
0
9
75
0
9
0
0
0
0
0
0
0
% G
% His:
9
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
9
59
59
0
9
9
0
% I
% Lys:
17
9
0
25
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
67
9
9
0
0
9
17
9
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
50
17
9
0
0
0
0
0
84
0
9
0
% P
% Gln:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
9
0
67
0
9
9
0
0
0
0
0
% R
% Ser:
9
0
0
9
0
9
0
0
0
0
0
0
17
0
0
% S
% Thr:
34
9
0
9
0
0
0
0
0
0
0
0
75
67
9
% T
% Val:
0
0
0
0
0
0
0
0
67
17
34
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
75
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _